Chen and team found that serotonin has a muddling effect on the sensation of pain and itch, whereby, as serotonin spreads from brain to spinal cord, pain-sensing neurons instead influence itch intensity. Based on our own experiences of chronic eczema , Medical News Today asked Dr.
The reason is that, at least from our studies in mice, when you scratch to create pain, the brain in response begins to produce more serotonin to inhibit pain the brain does not want to have pain in your body. What we found is that while serotonin inhibits itch, it also can activate the itch receptor and make more itching. The researchers bred mice that lacked the genes necessary for serotonin production.
When the serotonin-free mice were injected with a substance that would normally cause itching, the researchers found that the mice did not scratch as much as a control group of mice with the serotonin-producing genes. Next, the mice that lacked the serotonin genes were injected with serotonin. The injected serotonin caused the mice to scratch in a manner that was consistent with the control group.
The team considered different approaches that might be useful in minimizing the itching sensation. You can generally treat a rash with over-the-counter OTC remedies. However, there are rashes that a medical professional should look at. These rashes might be a sign of an infection, allergic reaction, or disease. You can read 12 common signs a rash might be a sign of something more serious below.
An area on your skin that is itchy, irritated, and swollen is called a rash. A rash can be raised, bumpy, blistered, or patchy. Rashes can present differently depending on your skin tone. People with lighter skin often see rashes that are pink, red, or purple. People with darker skin might develop rashes that are white, gray, or darker than the surrounding skin. Rashes are very common. Many types of rash are mild and can be treated with OTC medications. For example, contact dermatitis is a rash you get when your skin touches something that causes it to become itchy and irritated.
A contact dermatitis rash will be inflamed and itchy. It will generally be contained to the part of your skin that touched the irritant. Avoiding the item in the future and using an OTC anti-itch cream is normally enough to treat contact dermatitis. Sometimes, a rash is a sign something serious is going on with your body. Seek medical care if any of them develop.
A fever is a key sign that rash should be looked at by a doctor. It could be a sign of an allergic reaction. A fever along with your rash could also indicate an infection such as:. Urticaria and angioedema. In: Fitzpatrick's Dermatology in General Medicine.
New York, N. Adkinson NF, et al. In: Middleton's Allergy: Principles and Practice. Philadelphia, Pa. Amin P, et al. Investigation of patient-specific characteristics associated with treatment outcomes for chronic urticaria.
Related Dermatographia. Mayo Clinic Press Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.
Bedbugs, which are roughly the size of poppy seeds, can cause very visible and itchy welts and rashes. People who are highly sensitive or allergic to bed bugs may need antihistamines to reduce the itching. It usually takes professionals to remove bed bugs.
However, some of these methods may help. The scabies mite, which is invisible to the naked eye, can also cause an itchy rash.
A person can develop scabies after direct contact with a person who has the condition, or through contact with infected objects. Scabies is readily treated but requires prescription medication. Ringworm is a fungal infection that causes a circular, red, or brown itchy rash with a thicker edge. However, it can spread from one body part to another.
Some rashes, such as those due to poison ivy, will go away on their own. Others, such as psoriasis, tend to be a lifelong condition. There are many reasons why a person may have an itchy rash. It may be a side effect of a more severe underlying condition. A person should see a doctor if they are concerned about the cause of their rash. It is possible to manage most rashes, including those caused by more serious medical conditions, with medical treatment.
Herpes skin rash outbreaks usually affect the mouth or genitals, but they can appear anywhere on the body. Learn more about herpes skin rashes here. A range of viral infections, including shingles, chickenpox, and measles, can cause a skin rash. Learn more about the types, symptoms, and treatment…. Home remedies, such as cold compresses, calamine lotion, and oatmeal baths, can help soothe the symptoms of heat rash.
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